Scientists found that patients with inflammatory diseases often have higher PDE-4 levels compared to healthy individuals. There are also biologic treatments such as Humira, Cimzia, and Enbrel. They do that by decreasing the activity of the enzyme that modulates inflammation within cells.īefore Otezla was available, many patients were prescribed older medications to treat such conditions, including methotrexate, leflunomide, and sulfasalazine. PDE-4 inhibitors help your body lower inflammation. It belongs to the class of drugs called phosphodiesterase-4 (PDE-4) inhibitors. But now, Otezla is FDA-approved for use in adults for mild and moderate psoriasis, too. The Food and Drug Administration (FDA) approved Otezla in 2014, first for psoriatic arthritis and then for plaque psoriasis. Otezla is a relatively new drug that dominates its category. Patients typically prefer an oral medication over an injectable, so Otezla is able to command premium pricing. Alternative drugs for these conditions, such as Humira, must be taken by injection. That enables Amgen, the manufacturer, to keep its price high.Īlso, Otezla has a key advantage over many other psoriasis and arthritis medications: It comes in a convenient pill form. Otezla’s formula is still protected by patent, so it currently has no competition from generic versions. How much does a 30-day supply of Otezla cost?Īs of late 2021, the average cash price for Otezla was $6,503.57 for a 1-month supply of 30 mg tablets. Here's a closer look at how much Otezla costs and how you can save money on this costly but powerful medication. You may also have to get prior authorization or go through step therapy to get your insurance company to pay for this drug. Otezla is covered under most Medicare and insurance plans, but you may face a large deductible or copay. Otezla is one of the most popular brand-name drugs in the U.S. For some autoimmune disorders - psoriatic arthritis, plaque psoriasis, and certain mouth ulcers - doctors commonly prescribe Otezla. Between 5% to 8% of Americans suffer from autoimmune diseases, which often involve painful inflammation.
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